NORMAL STANDARDS OF GASTRIC FUNCTION
Open Access
- 1 February 1931
- journal article
- research article
- Published by American Society for Clinical Investigation in Journal of Clinical Investigation
- Vol. 9 (4) , 651-658
- https://doi.org/10.1172/jci100327
Abstract
In "normal" adult hospital patients (i.e., without digestive symptoms and secreting a juice with free HCl over 10), the fasting gastric juice was aspirated, 0.1 mgm. histamine per kgm. body weight was hypodermically injected, and the total secretions aspirated over successive 10-min. periods until the flow of juice had subsided to the basal level. The greatest 10-min. volume of secretion and the highest titratable acidity were considered indices of stomach function. Wide variations in volume were observed, with progressive decrease in amount with advancing age. About 1/2 determinations, however, fell within 21-35 cc. Considerable variation was also observed in highest titratable acidity; however, about 3/4 of the values lie above 100. The acid values show a decline with advancing age when the figures in various decades are averaged.This publication has 3 references indexed in Scilit:
- THE CHLORIDE, BASE AND NITROGEN CONTENT OF GASTRIC JUICE AFTER HISTAMINE STIMULATIONJournal of Clinical Investigation, 1928
- GASTRIC MOTILITY AND THE VOLUME OF GASTRIC SECRETION IN MANJournal of Clinical Investigation, 1928
- GASTRIC ACIDITY: RELATION TO VARIOUS FACTORS SUCH AS AGE AND PHYSICAL FITNESSJournal of Clinical Investigation, 1928