Evolutionary optimization of the catalytic effectiveness of an enzyme
- 1 November 1989
- journal article
- research article
- Published by American Chemical Society (ACS) in Biochemistry
- Vol. 28 (24) , 9293-9305
- https://doi.org/10.1021/bi00450a009
Abstract
Note: In lieu of an abstract, this is the article's first page.This publication has 6 references indexed in Scilit:
- Possible role for water dissociation in the slow binding of phosphorus-containing transition-state-analog inhibitors of thermolysinBiochemistry, 1987
- Reaction energetics of a mutant triose phosphate isomerase in which the active-site glutamate has been changed to aspartateBiochemistry, 1986
- Electrostatic influence on energetics of electron transfer reactions.Proceedings of the National Academy of Sciences, 1985
- Rate-limiting step: a quantitative definition. Application to steady-state enzymic systemsBiochemistry, 1983
- A mechanistic basis for the stereoselectivity of enzymic transfer of hydrogen from nicotinamide cofactorsJournal of the American Chemical Society, 1983
- The theory of reactions involving proton transfersProceedings of the Royal Society of London. Series A. Mathematical and Physical Sciences, 1936