Abstract
Sixteen new cases of the asplenia syndrome with autopsy findings had a female preponderance of 2:1. Racial incidence of splenic agenesis was 9 whites and 7 blacks. The average life span of the infants born alive was approximately 38 days. All infants with asplenia syndrome had recorded weights and lengths below normal standard values. Surgical palliation of the cardiovascular anomalies in the asplenia syndrome was attempted in 2 cases. The incidence of the asplenia syndrome from the large autopsy series was 1 case/2000 autopsies.

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