Stereoselective synthesis of HR 780 a new highly potent HMG-CoA reductase inhibitor

This publication has 12 references indexed in Scilit:

• Synthesis and biological activity of new HMG-CoA reductase inhibitors. 1. Lactones of pyridine- and pyrimidine-substituted 3,5-dihydroxy-6-heptenoic (-heptanoic) acids
  Journal of Medicinal Chemistry, 1990
• Lovastatin
  Drugs, 1988
• HMG-CoA Reductase Inhibitors for Treatment of Hypercholesterolemia
  New England Journal of Medicine, 1988
• A Novel Method for the In situ Generation of Alkoxydialkylboranes and Their Use in the Selective Preparation of 1,3-syn Diols
  Chemistry Letters, 1987
• 1,3- diastereoselective reduction of β-hydroxyketones utilizing alkoxydialkylboranes
  Tetrahedron Letters, 1987
• Synthesis of an HMG-CoA reductase inhibitor; a diastereoselective aldol approach
  Tetrahedron Letters, 1987
• COMBINATION OF BORANE-DIMETHYL SULFIDE COMPLEX WITH CATALYTIC SODIUM TETRAHYDROBORATE AS A SELECTIVE REDUCING AGENT FOR α-HYDROXY ESTERS. VERSATILE CHIRAL BUILDING BLOCK FROM (S)-(−)-MALIC ACID
  Chemistry Letters, 1984
• Catalyzed oxidation of alcohols and aldehydes with iodosylbenzene
  Tetrahedron Letters, 1981
• STEREOSELECTIVE SYNTHESIS OF MESO(OR ERYTHRO) 1,3-DIOLS FROM β-HYDROXYKETONES
  Chemistry Letters, 1980
• Oxidation of long-chain and related alcohols to carbonyls by dimethyl sulfoxide "activated" by oxalyl chloride
  The Journal of Organic Chemistry, 1978