Selective removal of the methyldiphenylsilyl protecting group using azide ion

1 January 1989

journal article
research article
Published by Royal Society of Chemistry (RSC) in Journal of the Chemical Society, Chemical Communications

No. 6,p. 381-382
https://doi.org/10.1039/c39890000381

Abstract

Sodium azide in dimethylformamide effects the cleavage of the methyldiphenylsilyl ether bond under conditions whereby t-butyldimethylsilyl ethers and t-butyldiphenylsilyl ethers are stable.

Keywords

SODIUM
REMOVAL
CLEAVAGE
DIMETHYLFORMAMIDE
BUTYLDIPHENYLSILYL
BOND
BUTYLDIMETHYLSILYL
AZIDE
METHYLDIPHENYLSILYL PROTECTING