Prolongation of Skin Homograft Survival in Rabbits by 6-Mercaptopurine.
- 1 November 1959
- journal article
- Published by Frontiers Media SA in Experimental Biology and Medicine
- Vol. 102 (2) , 459-461
- https://doi.org/10.3181/00379727-102-25284
Abstract
6-MP, a powerful metabolic antagonist to nucleic acid synthesis, prolongs survival time of skin homografts in rabbits when administered after grafting. Treatment must be given continuously to maintain graft viability. However, toxicity of 6-MP limits the length of time treatment may be given.Keywords
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