Spiro[isobenzofuran-1(3H),4'-piperidines]. 3. Diuretic and antihypertensive properties of compounds containing a sulfur attached to nitrogen

Abstract
The synthesis and antihypertensive and diuretic activity of several N-sulfur derivatives of 3-phenylspiro[isobenzofuran-1(3H),4''-piperidine] are reported. Benzenesulfenamide possessed marked, species-specific diuretic and antihypertensive activity in rats.