The influence of age on the intestinal absorption of 47-Ca absorption in post-menopausal osteoporosis.

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Abstract
The intestinal absorption of orally administered 47Ca has been quantitated in 59 normal female subjects, aged 12-85 yr. and in 16 postmenopausal osteoporotic women after adjustments to low Ca intakes. A significant inverse correlation between 1-hr. plasma 47Ca levels and age was observed. Patients with ostoeporosis demonstrated a normal 47Ca absorption pattern when compared to 15 age-matched non-osteoporotic controls with no significant differences in 1-hr. plasma 47Ca levels or cumulative 12 -day fecal 47Ca excretion. The implications of these findings and their correlation with age dependent changes in bone density are discussed.