Variants of N-tropic leukemia virus derived from BALB/c mice
- 1 October 1975
- journal article
- research article
- Published by American Society for Microbiology in Journal of Virology
- Vol. 16 (4) , 991-999
- https://doi.org/10.1128/jvi.16.4.991-999.1975
Abstract
Clonal lines derived from cultures of NIH/3T3 cells infected with N-tropic leukemia virus from BALB/c mice differ in the amount and type of N-tropic virus they produce. Three biologically distinguishable N-tropic viruses were found: the large XC plaque-forming virus of hartley et al. (1969) (LP-N), A SMALL XC plaque-forming virus (sp-n), and a non-plaque-forming virus (NP-N). SP-N and NP-N are less infectious than LP-N. Upon prolonged passage in NIH/3T3 cells NP-N gives rise to highly infectious LP-N.Keywords
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