CORRELATION BETWEEN TUBOCURARINE REQUIREMENTS AND PLASMA PROTEIN PATTERN
Open Access
- 1 February 1968
- journal article
- research article
- Published by Elsevier in British Journal of Anaesthesia
- Vol. 40 (2) , 89-93
- https://doi.org/10.1093/bja/40.2.89
Abstract
The correlation between tubocurarine requirements and the electrophoretic serum protein pattern was investigated in 52 adult patients undergoing upper abdominal surgery under nitrous oxide and oxygen anaesthesia. There was a positive correlation between the tubocurarine requirements (mg/kg) and the serum level of gamma globulin; r= +0.604, which is highly significant (P<0.001). This correlation is attributed to the ability of gamma globulin to bind tubocurarine. The plasma gamma globulin level appears to be one of the factors which might determine tubocurarine requirements.Keywords
This publication has 0 references indexed in Scilit: