Compartmental vs. noncompartmental modeling for two accessible pools
- 1 September 1984
- journal article
- research article
- Published by American Physiological Society in American Journal of Physiology-Regulatory, Integrative and Comparative Physiology
- Vol. 247 (3) , R488-R496
- https://doi.org/10.1152/ajpregu.1984.247.3.r488
Abstract
We examine the limitations of noncompartmental vs. compartmental modeling when two accessible pools are available in kinetic experiments. Focus is on the estimation of mean residence time, whole-body mass, and steady-state equivalent distribution volume. Examples illustrate these points.This publication has 4 references indexed in Scilit:
- Multiexponential, multicompartmental, and noncompartmental modeling. I. Methodological limitations and physiological interpretationsAmerican Journal of Physiology-Regulatory, Integrative and Comparative Physiology, 1984
- Model of the kinetics of ketone bodies in humansAmerican Journal of Physiology-Regulatory, Integrative and Comparative Physiology, 1982
- Residence times in compartmental systems with and without inputsMathematical Biosciences, 1981
- Stochastic parameters in compartmental systemsMathematical Biosciences, 1980