Intracoronary Enalaprilat Improves Metabolic Coronary Vasodilation in Patients with Idiopathic Dilated Cardiomyopathy
- 1 February 2000
- journal article
- research article
- Published by Wolters Kluwer Health in Journal of Cardiovascular Pharmacology
- Vol. 35 (2) , 249-255
- https://doi.org/10.1097/00005344-200002000-00011
Abstract
Coronary flow reserve is reduced in patients with idiopathic dilated cardiomyopathy (DCM). We examined acute effects of intracoronary enalaprilat on metabolic coronary vasodilation during pacing tachycardia in patients. Coronary blood flow (Doppler guidewire) and diameter (quantitative angiography) were measured in seven patients with DCM and seven control subjects. In the DCM group, tachypacing increased coronary blood flow by 37 ± 22% from the baseline before enalaprilat and by 65 ± 22% (p NKeywords
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