THE PHARMACOLOGICAL ACTIVITY OF CANNABINOL AND ITS MAJOR METABOLITE, 11-HYDROXYCANNABINOL
- 1 January 1987
- journal article
- research article
- Published by Pharmaceutical Society of Japan in CHEMICAL & PHARMACEUTICAL BULLETIN
- Vol. 35 (5) , 2144-2147
- https://doi.org/10.1248/cpb.35.2144
Abstract
The pharmacological effects (catalepsy, hypothermia, pentobarbital-induced sleep prolongation and effect on locomotor activity) of cannabinol and its major metabolite, 11-hydroxycannabinol were studied in mice. 11-Hydroxycannabinol was more potent than cannabinol in the pharmacological indices examined. The results indicate that 11-hydroxycannabinol can be categorized as an active metabolite of cannabinol.This publication has 4 references indexed in Scilit:
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