12-O-tetradecanoylphorbol-13-acetate (TPA) Inhibits Osteoclastogenesis by Suppressing RANKL-Induced NF-κB Activation
Open Access
- 1 December 2003
- journal article
- research article
- Published by Oxford University Press (OUP) in Journal of Bone and Mineral Research
- Vol. 18 (12) , 2159-2168
- https://doi.org/10.1359/jbmr.2003.18.12.2159
Abstract
The mechanism by which TPA-induced PKC activity modulates osteoclastogenesis is not clear. Using a RAW264.7 cell culture system and assays for NF-κB nuclear translocation, NF-κB reporter gene activit...Keywords
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