Metabolism of halohydroquinones inRhodococcus chlorophenolicus PCP-1
- 1 June 1995
- journal article
- research article
- Published by Springer Nature in Biodegradation
- Vol. 6 (2) , 119-126
- https://doi.org/10.1007/bf00695342
Abstract
The actinomyceteRhodococcus chlorophenolicus PCP-1 metabolises pentachlorophenol into ultimate inorganic end products via tetrachloro-p-hydroquinone. This intermediate was further dehalogenated in the cytoplasm requiring reductant in the cell free system. Tetrafluoro-p-hydroquinone and tetrabromo-p-hydroquinone were also dehalogenated. Chlorophenol analogs, thiol blocking agents and molecular oxygen inhibited the activity. The dehalogenating reactions led to 1,2,4-trihydroxybenzene, which was further metabolized into maleic acid.Keywords
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