Response of human forearm muscle blood vessels to hyperventilation

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Abstract
The effect of hyperventilation on circulation through skeletal muscle was evaluated before and after total nerve block. Distribution of forearm blood flow was judged from measurements by the counter pressure modification of the capacitance plethysmograph technique and estimated for deep and superficial oxygen tension determinations made before, during and after 3 min of voluntary hyperventilation. These criteria indicate a marked increase in blood flow through muscle in both the intact and nerve blocked forearm, but no significant change inflow through the superficial tissues. It is concluded that the hyperaemia is the result of a combination of influences originating from central chemoreceptors and local effects.

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