Het Regeneratie Vermogen En De Reserve Capaciteit Van De Lever En Het Mogelijk Nut Daarvan Voor De Chirurgie Der Galwegen Door

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Abstract
1° It is experimentally demonstrated that by stopping the bile-flow from a great part of the liver to the bowel in pigs and rabbits no icterus is produced, and that this condition is compatible with normal life. 2° Furthermore it is established that the bile (eventually produced in these obstructed parts of the liver) cannot possibly escape through intrahepatic anastomoses of bile ducts (or biliary ducts ?). 3° The parts of the liver in which the bile flows freely, become hyper- functional and assume entirely the assimilation of bilirubine. 4° Is was established that the parts with obstructed bile ducts undergo atrophy, while a compensatory hypertrophy occurs in those where the bile can 5° It is likely that these facts apply equally to man. 6 This aspect of hepatic physiology has its surgical applications : a) it is possible to ligature high up in the hepatic hilus and a branch can be used for plastic interventions on the common bileduct; b) anastomosis with one of the branches of the hepatic duct is a very satisfactory intervention; c) when circumstances require it absolutely, one is justified to sacrifice one branch of the hepatic duct.
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