Portable, high-bandwidth frequency-domain photon migration instrument for tissue spectroscopy
Open Access
- 1 December 1994
- journal article
- Published by Optica Publishing Group in Optics Letters
- Vol. 19 (23) , 1934-1936
- https://doi.org/10.1364/ol.19.001934
Abstract
We describe a novel frequency-domain photon migration instrument employing direct diode laser modulation and avalanche photodiode detection, which is capable of noninvasively determinating the optical properties of biological tissues in near real time. An infinite medium diffusion model was used to extract absorption and transport scattering coefficients from 300-kHz to 800-MHz photon-density wave phase data. Optical properties measured in tissue-simulating solutions at 670 nm agreed to within 10% of those expected.Keywords
This publication has 7 references indexed in Scilit:
- Determination of the optical properties of the human uterus using frequency-domain photon migration and steady-state techniquesPhysics in Medicine & Biology, 1994
- The measured electrical properties of normal and malignant human tissues from 50 to 900 MHzMedical Physics, 1994
- Properties of photon density waves in multiple-scattering mediaApplied Optics, 1993
- Refraction of diffuse photon density wavesPhysical Review Letters, 1992
- Optical properties of intralipid: A phantom medium for light propagation studiesLasers in Surgery and Medicine, 1992
- Light scattering in lntralipid-10% in the wavelength range of 400–1100 nmApplied Optics, 1991
- Large signal nonlinear distortion prediction for a single-mode laser diode under microwave intensity modulationJournal of Lightwave Technology, 1987