Positive control and autogenous regulation of the nifLA promoter in Klebsiella pneumoniae

Abstract
The N fixation (nif) genes of K. pneumoniae are specifically regulated by the products of the nifLA operon. The promoter of this operon was located and sequences required for nifLA transcription were identified. Transcription from this promoter is shown to be positively regulated by the ntrC gene product (which coordinates the expression of many operons required for N assimilation) and also autogenously by the product of the nifA gene.

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