Simple Method for Enhancing Development of Acute Disseminated Encephalomyelitis in Mice.
- 1 June 1955
- journal article
- research article
- Published by Frontiers Media SA in Experimental Biology and Medicine
- Vol. 89 (2) , 263-266
- https://doi.org/10.3181/00379727-89-21778
Abstract
Conclusion By manipulations here described it was possible to induce acute disseminated encephalomyelitis in mice in a shorter time than heretofore, with fewer inoculations and with uniform response. The improved method consists of the intraperitoneal injection of H. pertussis vaccine followed by 2 spaced intracutaneous injections of proteolipide A + B prepared in a Freund-type adjuvant.Keywords
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