Changes in the brainstem evoked responses following jugular vein ligation

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Abstract
Blockage of both jugular veins is often followed by signs of intracranial hypertension. The use of brainstem evoked responses (BSER) in the detection of brainstem compression following jugular vein ligation in guinea pigs was studied. Thirty pigmented guinea pigs were studied. Unilateral jugular vein ligation was performed in 10 animals and bilaterally in 10. Ten animals were controls. The BSER to clicks at 20 db above hearing thresholds before and 6 hours following ligation of one or both jugular veins were recorded. No change in the hearing threshold was observed following jugular vein(s) ligation. However, prolongation of the I-III and III-IV interpeak intervals were observed following both unilateral and bilateral jugular vein ligation. The results suggest that BSER monitoring may be useful in the early detection of brainstem compression following jugular vein ligation in head and neck surgery.