Translation in vitro of RNA from the human malarial parasite Plasmodium falciparum
- 1 September 1982
- journal article
- research article
- Published by Portland Press Ltd. in Bioscience Reports
- Vol. 2 (9) , 667-673
- https://doi.org/10.1007/bf01114828
Abstract
RNA was isolated from the human malarial parasite, P. falciparum, and translated in vitro using 2 systems: rabbit-reticulocyte lysate and Xenopus laevis oocytes. Polypeptides are synthesized that are characteristic of the parasite isolate and the developmental stage from which the RNA was purified. Many of these polypeptides are precipitated by antibody from an immune monkey. Analysis of the primary structure of these polypeptides should give the information necessary to produce a vaccine against this parasite.This publication has 20 references indexed in Scilit:
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