Necic acid synthons. Part 5. Total synthesis of (±)-retronecic acid and related compounds via zinc-mediated coupling of halogeno-esters
- 1 January 1985
- journal article
- research article
- Published by Royal Society of Chemistry (RSC) in Journal of the Chemical Society, Perkin Transactions 1
- p. 2713-2717
- https://doi.org/10.1039/p19850002713
Abstract
Zinc-mediated coupling of suitably substituted halogeno esters affords access to (±)-retronecic acid (2) and related intermediates. These approaches lead to racemic retronecic acid on the one hand and to a diastereoisomeric mixture of the acid on the other.Keywords
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