Novel Synthesis of Disubstituted Alkyne Using Molybdenum Catalyzed Cross-Alkyne Metathesis

Abstract
A novel disubstituted alkyne synthesis was developed using molybdenum catalyzed cross-alkyne metathesis by Mortreux’s catalyst [Mo(CO)6-p-ClC6H4OH]. The reaction was carried out using Mo(CO)6 (5 mol% for total amounts of alkynes) and p-ClC6H4OH (1 equiv.) in the presence of an excess amount of another alkyne (3∼11 equiv.) in refluxing toluene.