Failure of high-dose heparin to prevent recurrent cardioembolic strokes in a pregnant patient with a mechanical heart valve
- 1 November 1992
- journal article
- case report
- Published by Wolters Kluwer Health in Neurology
- Vol. 42 (11) , 2204
- https://doi.org/10.1212/wnl.42.11.2204
Abstract
A 27-year-old woman with a mechanical heart valve suffered multiple thromboembolic events while pregnant despite anticoagulation with high-dose heparin. Warfarin, the anticoagulant of choice for patients with prosthetic heart valves, is ter-atogenic and can cause hemorrhagic complications at delivery. Heparin reduces thromboembolic complications, but is of uncertain efficacy. We discuss alternatives for the prevention of thromboembolic complications in pregnant women with mechanical heart valves.Keywords
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