Native extracellular matrix coating on Ti surfaces
- 10 July 2003
- journal article
- research article
- Published by Wiley in Journal of Biomedical Materials Research Part A
- Vol. 66A (2) , 310-316
- https://doi.org/10.1002/jbm.a.10575
Abstract
Osteoblast-like SAOS-2 cells were allowed to synthesize and assemble their extracellular matrix (ECM) on titanium surfaces. After the selective removal of cells, Ti coated with a native ECM was obtained (ECM-Ti). The responses of SAOS-2 cells to ECM−Ti compared with those to peptide sequence RGDS- or fibronectin-immobilized Ti were examined, demonstrating the compositional and structural effects needed to trigger the native cell behavior. © 2003 Wiley Periodicals, Inc. J Biomed Mater Res 66A: 310–316, 2003Keywords
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