Effect of mutations found in carbohydrate‐deficient glycoprotein syndrome type IA on the activity of phosphomannomutase 2
Open Access
- 11 June 1999
- journal article
- Published by Wiley in FEBS Letters
- Vol. 452 (3) , 319-322
- https://doi.org/10.1016/s0014-5793(99)00673-0
Abstract
Seven mutant forms of human phosphomannomutase 2 were produced in Escherichia coli and purified. These mutants had a V max of 0.2–50% of the wild enzyme and were unstable. The least active protein (R...Keywords
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