Androgenic control of N-acetyltransferase activity in the harderian glands of the syrian hamster is mediated by 5?-dihydrotestosterone
- 19 February 1990
- journal article
- research article
- Published by Wiley in Journal of Cellular Biochemistry
- Vol. 42 (2) , 95-100
- https://doi.org/10.1002/jcb.240420205
Abstract
N‐acetyltransferase (NAT) activity in the Harderian glands of intact and gonadectomized male and female Syrian hamsters was evaluated. The exogenous administration of 5α‐dihydrotestosterone (DHT) to castrated males and intact females produced an increase in NAT values, which reached the values present in the glands of intact males. The administration of a 5α‐reductase inhibitor to intact males led to a decrease in NAT activity, suggesting that testosterone is converted in DHT within the glands. It is concluded that NAT activity in the Syrian hamster Harderian glands is under androgenic control, the active steroid being DHT.Keywords
This publication has 16 references indexed in Scilit:
- N-acetyltransferase activity and indole contents of the male syrian hamster harderian gland: Changes during the light:dark cycleArchives of Biochemistry and Biophysics, 1989
- Androgenic control of immunoreactive somatostatin in the Harderian gland of the Syrian hamsterReproduction, 1988
- Sexual Dimorphism in N-Acetyltransferase Activity, Hydroxyindole-O-methyltransferase Activity, and Melatonin Content in the Harderian Gland of Syrian Hamsters: Changes following GonadectomyExperimental Biology and Medicine, 1988
- N-Acetyltransferase activity, hydroxyindole-O-methyltransferase activity, and melatonin levels in the Harderian glands of the female Syrian hamster: Changes during the light: Dark cycle and the effect of 6-parachlorophenylalanine administrationBiochemical and Biophysical Research Communications, 1987
- Harderian Glands of Golden Hamsters: Temporal and Sexual Differences in Immunoreactive MelatoninJournal of Pineal Research, 1985
- Harderian Gland: Regulation of Sexual “Type” by Gonads and Pineal GlandBiology of Reproduction, 1984
- Concurrent determination of enzymatic activities and substrate concentrations in the melatonin synthetic pathway within the same rat pineal glandJournal of Neuroscience Research, 1984
- ANDROGENIC CONTROL OF THE HARDERIAN GLAND IN THE MALE GOLDEN HAMSTERJournal of Endocrinology, 1977
- Effects of Castration, Blinding, and the Pineal Gland on the Harderian Glands of the Male Golden HamsterNeuroendocrinology, 1973
- Influence of some endocrine glands, hormones and blinding on the histology and porphyrins of the Harderian glands of golden hamstersJournal of Anatomy, 1971