Treatment of Cyclical Breast Pain with Bromocriptine

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Abstract
Bromocriptine 2.5 mg. twice daily was given to 38 patients with cyclical breast pain and 15 with a non-cyclical pattern in a double blind trial lasting 6 cycles. Response to treatment was assessed by both clinician and patients independently and serum prolactin levels were monitored. Cyclical breast pain was significantly improved by bromocriptine but non-cyclical pain failed to respond. Although most patients were normoprolactinaemic before the trial, bromocriptine therapy produced a significant depression of the mean serum prolactin level.