A Controlled Trial of Ganciclovir to Prevent Cytomegalovirus Disease after Heart Transplantation
Open Access
- 30 April 1992
- journal article
- research article
- Published by Massachusetts Medical Society in New England Journal of Medicine
- Vol. 326 (18) , 1182-1186
- https://doi.org/10.1056/nejm199204303261803
Abstract
Because of the immunosuppression required, heart-transplant recipients frequently have complications caused by cytomegalovirus (CMV), including pneumonia, esophagitis, gastritis, and a syndrome of fever, hepatitis, and leukopenia. We undertook a controlled trial to evaluate the prophylactic administration of ganciclovir to prevent CMV-induced disease after heart transplantation.Keywords
This publication has 16 references indexed in Scilit:
- A Randomized, Controlled Trial of Prophylactic Ganciclovir for Cytomegalovirus Pulmonary Infection in Recipients of Allogeneic Bone Marrow TransplantsNew England Journal of Medicine, 1991
- Cytomegalovirus infection is associated with cardiac allograft rejection and atherosclerosisJAMA, 1989
- GANCICLOVIR/IMMUNOGLOBULIN COMBINATION THERAPY FOR THE TREATMENT OF HUMAN CYTOMEGALOVIRUS-ASSOCIATED INTERSTITIAL PNEUMONIA IN BONE MARROW ALLOGRAFT RECIPIENTSTransplantation, 1988
- Treatment of Cytomegalovirus Pneumonia with Ganciclovir and Intravenous Cytomegalovirus Immunoglobulin in Patients with Bone Marrow TransplantsAnnals of Internal Medicine, 1988
- Long-term acyclovir suppression of frequently recurring genital herpes simplex virus infection. A multicenter double-blind trialJAMA, 1988
- Antiviral Activity and Mechanism of Action of GanciclovirClinical Infectious Diseases, 1988
- Ganciclovir Treatment of Life- or Sight-Threatening Cytomegalovirus Infection: Experience in 314 Immunocompromised PatientsClinical Infectious Diseases, 1988
- Treatment of Serious Cytomegalovirus Infections with 9-(1,3-Dihydroxy-2-Propoxymethyl)Guanine in Patients with AIDS and Other ImmunodeficienciesNew England Journal of Medicine, 1986
- Specific cell-mediated immunity and infections with herpes viruses in cardiac transplant recipientsThe American Journal of Medicine, 1982
- Increased Pulmonary Superinfections in Cardiac-Transplant Patients Undergoing Primary Cytomegalovirus InfectionNew England Journal of Medicine, 1978