MORPHOLOGICAL CEREBRAL ASYMMETRIES IN AUTISTIC-CHILDREN

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  • 1 January 1983
    • journal article
    • research article
    • Vol. 18  (3) , 317-327
Abstract
Children (36) with infantile autism and various neurological disorders matched closely on age, sex and handedness underwent computerized tomographic (CT) scanning of the brain. All CT scans were assessed blindly and independently by a neuroradiologist. Two techniques modified from 2 published CT studies concerning cerebral asymmetries were used for measuring frontal and parieto-occipital asymmetries. The CT pattern of cerebral asymmetries in autistic children is the same as observed in the neurological patients. Contradictory results were noted when the distribution of such asymmetries between the present autistic group and normal adults included in 2 previous studies were compared. The brains of the present autistic patients seem to be more symmetric than those of the normals. This finding is also noted in the present matched controls as well as in the dyslexic children previously studied by other investigators. Further sophisticated studies are needed to explain the difference in the brain morphology between normals and children with a developmental disorder or a neurological disorder.

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