Prolongation of Islet Allograft Survival Following in Vitro Culture (24°C) and a Single Injection of ALS
- 20 April 1979
- journal article
- research article
- Published by American Association for the Advancement of Science (AAAS) in Science
- Vol. 204 (4390) , 312-313
- https://doi.org/10.1126/science.107588
Abstract
Isolated rat islets remain morphologically and functionally intact during a 7-day period of in vitro culture at 24 degrees C. In vitro culture of islets at 24 degrees C for 7 days prior to transplantation, in conjunction with a single injection of antiserum to lymphocytes into the diabetic recipient, results in islet allograft survival of 100 days when the islets are transplanted across a major histocompatibility barrier.This publication has 9 references indexed in Scilit:
- PROLONGATION OF ISLET ALLOGRAFT SURVIVALTransplantation, 1979
- MECHANISM OF THYROID ALLOGRAFT REJECTIONImmunology & Cell Biology, 1976
- Activation of Transplant Immunity: Effect of Donor Leukocytes on Thyroid Allograft RejectionScience, 1976
- Thyroid Allograft Immunogenicity Is Reduced After a Period in Organ CultureScience, 1975
- Lymphocyte Antigenicity Loss with Retention of ResponsivenessScience, 1974
- Effect of transplantation site on the results of pancreatic islet isografts in diabetic ratsDiabetologia, 1973
- Perifusion of Isolated Rat Islets in Vitro: Participation of the Microtubular System in the Biphasic Release of InsulinDiabetes, 1972
- Immunoassayable Insulin Content of Subcellular Fractions of Rat Islets1Endocrinology, 1969
- Method for the Isolation of Intact Islets of Langerhans from the Rat PancreasDiabetes, 1967