Autoradiographic Localization of Fluoride and Calcium Deposition in the Atherosclerotic Aorta of Cholesterol-Fed Rabbits

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Abstract
In autoradiographic investigations on rabbits with induced dietary atherosclerosis the uptake of F18 and Ca45 in the aorta wall was found to coincide with each other and with the structures where precipitated calcium phosphate could be demonstrated by von Kossa staining. These findings, together with data quoted from the literature, indicate that the relatively high fluoride concentrations often found in the aorta are secondary to atherosclerotic calcification and of no pathogenic significance.

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