Serienangiographische Studien über die Wirkungen des Histamin, Serotonin und der Substanz 48/80 auf den Leberkreislauf von Ratten und Meerschweinchen

Abstract
By injection of Thorotrast (which by itself does not affect blood vessels) after histamine into the cannulated portal artery, it could be shown that 100 - 800 [mu]g of histamine causes narrowing of the hepatic vessels, whereas 2.5 to 60 [mu]g produced no effect in the rat. Serotnin has a similar effect in both guinea pigs (above 40 [mu]g) and rats (above 5 [mu]g/animal). Substance 48/80 also caused vascular contraction in both guinea pigs (above 400 [mu]g) and rats (above 100 [mu]g).

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