Ferrocene‐Derived Pyrazinoyl and Nicotinoyl Schiff‐Bases: TheirSynthesis, Characterization and Biological Properties
Open Access
- 1 January 1999
- journal article
- research article
- Published by Wiley in Metal-Based Drugs
- Vol. 6 (3) , 149-152
- https://doi.org/10.1155/mbd.1999.149
Abstract
A novel class of acetylferrocene-derived Schiff-bases such as 2-pyrazinoyl-1-(2-ferroceneylmethylene)- hydrazide (HL1) and 2-nicotinoyl-1-(2-ferrocenylmethylene)hydrazide (HL2) have been synthesized and characterized by their IR, H1 NMR, C13 NMR and microanalytical date. The biological effect induced due to the coupling of ferrocene molecule with the aroylhydrazines e.g., pyrazinoylhydrazine and nicotinoylhydrazine has been studied against bacterial species such as Escherichia coli, Pseudomonas aeruginosa , Staphylococcus aureus and Klebsiella pneumonae.Keywords
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