Intrinsic Neuronal Determinants Locally Regulate Extrasynaptic and Synaptic Growth at the Adult Neuromuscular Junction
Open Access
- 10 February 1997
- journal article
- Published by Rockefeller University Press in The Journal of cell biology
- Vol. 136 (3) , 679-692
- https://doi.org/10.1083/jcb.136.3.679
Abstract
Long-term functional plasticity in the nervous system can involve structural changes in terminal arborization and synaptic connections. To determine whether the differential expression of intrinsic neuronal determinants affects structural plasticity, we produced and analyzed transgenic mice overexpressing the cytosolic proteins cortical cytoskeleton–associated protein 23 (CAP-23) and growth-associated protein 43 (GAP-43) in adult neurons.Keywords
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