pH CHANGES IN ISCHEMIC HUMAN MUSCLE AFTER VOLUNTARY CONTRACTION

Publisher Website
Google Scholar
Abstract
PH of intercellular fluid of voluntary muscle of unanesthe-tized human subjects was detd. with capillary glass electrode. (For technique B. A.[long dash]12, 729, May, 1938.) Ischemic in the resting muscle resulted in no fall of pH greater than 0.06 pH in 5 to 10 mins. in 7 subjects. After ischemic work and restoration of blood supply acidification of the intercellular fluid continued on the avg. for 23 secs. after ischemic pain was relieved (17 trials in 7 subjects). The degree of acidification of the non ischemic extensor digit. communis, after it had done work in the ischemic state, is tabulated: In general less than 100 Kg. cm. produced less than 0.1 pH change; from 100 to 200 Kg cm. from 0.1 to 02 pH change; from 200 to 300 Kg cm. from 0.2 to 0.3 pH change. All these trials reached the pain level. Recovery to resting pH value required from 1 to 30 mins. The pattern of pH change in human muscle after work and the implications from these data as to the causation of ischemic pain are discussed. It is deemed unlikely that the ischemic pain factor can be intercellular pH change (cf. B. A. 12, 6429, July, 1938).

This publication has 0 references indexed in Scilit: