Predominance of normal karyotype in colorectal tumors from hereditary non‐polyposis colorectal cancer patients
- 1 November 1995
- journal article
- research article
- Published by Wiley in Genes, Chromosomes and Cancer
- Vol. 14 (3) , 223-226
- https://doi.org/10.1002/gcc.2870140312
Abstract
We report the cytogenetic study of 9 colorectal tumors arising in patients with hereditary non‐polyposis colorectal cancer (HNPCC). According to the cytogenetic classification of colorectal tumors previously proposed by us, 2 cases were of the trisomic type, 2 were of the monosomic type, and 5 had a normal karyotype. This represents a significant excess of tumors with normal karyotype in HNPCC tumors (56%) compared to sporadic cases (10/184 = 5%).Keywords
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