Tracer Studies with Radioactive Sodium in Patients with Peripheral Vascular Disease

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Abstract
Radioactive Na was prepared by bombarding Na metaborate with deuterons in a cyclotron. The metaborate was dissolved in water, acidified and treated with methyl alc. NaCl was recovered after volatilization of other substances, and was made sterile for inj. Its circulation time was detd. with a Geiger-Miiller counter. The avg. value from arm to foot was 45 secs. with wide variation. In peripheral vascular disease, the time changes significantly, and so does the curve of "equilibrium buildup," i.e., the equilibrium resulting from Na exchange between plasma and extravascular fluid. Fifty patients have been studied.

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