Interferon Production in Children with Respiratory Diseases
- 21 January 1985
- journal article
- research article
- Published by Wiley in Acta Paediatrica
- Vol. 74 (1) , 118-121
- https://doi.org/10.1111/j.1651-2227.1985.tb10931.x
Abstract
In 110 children aged between 6 mo. and 18 yr the ability of leukocytes to produce the leukocyte interferon (IFN-.alpha.) in vitro was studied. The decrease or disappearance of IFN-.alpha. production was observed in some children with chronic or repeated respiratory diseases and in the majority of children who had been treated with prednisone. Increased production of IFN-.alpha. was found in a child with hypogammaglobulinemia and bronchopneumonia. In children affected by allergic or autoimmune diseases or bacterial infections IFN-.alpha. production was mostly normal. Age and sex had no influence on the production of IFN-.alpha.Keywords
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