Systemic lupus erythematosus in pregnancy treated with plasmapheresis

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Abstract
A young woman developed severe systemic lupus erythematosus (SLE) at the beginning of her 2nd pregnancy; her disease was extremely difficult to control and the baby died unexpectedly when 8 wk old. She became very ill at the same period in her 3rd pregnancy; plasmapheresis appeared to make her management easier and the 7 mo. old baby is doing well. Initially plasma exchange was considered most successful in those with acute SLE who have immune complexes in the serum; this patient had no detectable immune complexes.

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