CONJUGAL FERTILITY ASSOCIATED WITH RESISTANCE FACTOR R IN ESCHERICHIA COLI

Publisher Website
Google Scholar
Abstract
Sugino, Yoshinobu (Osaka University, Osaka, Japan) and Yukinori Hirota . Conjugal fertility associated with resistance factor R in Escherichia coli . J. Bacteriol. 84: 902–910. 1962.—The introduction of the contagious drug-resistance factor, R, into an F − strain of Escherichia coli allows the R + F − strain to mate with F − R − strains. The chromosome fragment transferred from the R + cell is relatively large, comparable to the conjugation between F + or Hfr male and F − female bacteria. The complex R factor has been analyzed by transduction with phage Pl. Within the R factor, the fertility determinant is inseparable from the determinant responsible for its infectivity, but can be separated from the loci for drug resistance. R thus resembles the category of complex F factors (F-primes) previously analyzed.