Secondary Hyperparathyroidism in Patients with Endemic Skeletal Fluorosis
- 17 March 1973
- Vol. 1 (5854) , 637-640
- https://doi.org/10.1136/bmj.1.5854.637
Abstract
Investigation of 20 patients with skeletal fluorosis showed that five had clear evidence of secondary hyperparathyroidism. The hyperactivity of the parathyroid glands in skeletal fluorosis in the presence of decreased solubility of the bone mineral (fluoroapatite) strongly suggests that it is a compensatory attempt to maintain a normal extracellular ionized calcium equilibrium. Further study of the parathyroid glands and of bone lesions in skeletal fluorosis is in progress.Keywords
This publication has 10 references indexed in Scilit:
- Endemic skeletal fluorosisArchives of Disease in Childhood, 1971
- Fluoride and boneCalcified Tissue International, 1969
- Tertiary HyperparathyroidismBMJ, 1968
- Use of Sodium Fluoride in the Treatment of OsteoporosisJournal of Clinical Endocrinology & Metabolism, 1967
- THE EFFECT OF COPPER AND FLUORIDE ON THE BONE OF MICE TREATED WITH PARATHYROID HORMONEJournal of Endocrinology, 1966
- Effect of Sodium Fluoride on the Ultra-structure of the Parathyroid Glands of the SheepNature, 1965
- Fluoride: Its Effects on Two Parameters of Bone Growth in Organ CultureScience, 1964
- Effects of Sodium Fluoride on Calcium Homeostasis.Experimental Biology and Medicine, 1964
- The effect of fluoride on the citrate content of the bones of the growing ratArchives of Oral Biology, 1963
- Skeletal lesions following ingestion of fluoridated waterCellular and Molecular Life Sciences, 1960