Cadmium uptake in Anacystis nidulans: Effect of modifying factors.

Abstract
Cd2+ uptake rates in the cyanobacterium A. nidulans IU 625 (ATCC 27144) were found to be concentration-dependent. While Ca2+ and Zn2+ showed competitive inhibition, Hg2+ enhanced Cd2+ uptake. The pH values optimal for growth of the organism (pH 8.5) resulted in more Cd2+ uptake than low (pH 6.5) or high pH (10.0) conditions. Dithiol (dithiothreitol) proved more effective in lessening Cd2+ uptake than monothiol (mercaptoethanol). The test organism suspended in spent medium showed negligible Cd2+ uptake. Among the synthetic complexans, EDTA inhibited metal uptake, while citrate favored the process. There was more Cd2+ uptake by dense cultures, but the specific rate expressed per unit protein was less.

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