Identification of a novel aminonucleoside produced by Enterobacter sp. as 2'-amino-2'-deoxyguanosine.
- 1 January 1976
- journal article
- research article
- Published by Pharmaceutical Society of Japan in CHEMICAL & PHARMACEUTICAL BULLETIN
- Vol. 24 (12) , 2955-2960
- https://doi.org/10.1248/cpb.24.2955
Abstract
A novel guanosine analog, aminonucleoside antibiotic (2AG), produced by Enterobacter sp., was identified as 9-(2''-amino-2''-deoxy-.beta.-D-ribofuranosyl)-guanine (2''-amino-2''-deoxyguanosine) by PMR and 13C NMR spectra of 2AG and acetylated 2AG, and also by the comparison of the aminosugar obtained by hydrolysis of 2AG with 2-amino-2-deoxypentoses. This is the 1st report on the occurrence of 2-amino-2-deoxy-D-ribose in nature.This publication has 4 references indexed in Scilit:
- Analogs of the Aminonucleoside Derived from Puromycin. The Synthesis of 3'-Amino-3'-deoxyguanosine and 3'-Amino-3'-deoxycrotonosideJournal of Medicinal Chemistry, 1963
- SYNTHESIS OF A BETA-1, 3-LINKED GLUCAN BY EXTRACTS OF PHASEOLUS-AUREUS SEEDLINGS1958
- A MODIFIED COLORIMETRIC METHOD FOR THE ESTIMATION OF N-ACETYLAMINO SUGARSJournal of Biological Chemistry, 1955
- A colorimetric method for the determination of glucosamine and chondrosamineBiochemical Journal, 1933