Of Men and Mitochondria — Intracellular and Subcellular Acid-Base Relations

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Abstract
THIS paper deals with one small aspect of the general problem that concerns the relation between organisms and their environment. Current concepts concerning this interrelation spring from the work of 3 men — an Englishman, a Frenchman and an American.The Englishman was, of course, the great British biologist, Charles Darwin, who developed the thesis that the external environment, in the last analysis, determines the nature of the organism. Specifically, he demonstrated that the external forms of organisms seem to be best explained as adaptations subserving the function of permitting survival in the face of vicissitudes and changes occurring in . . .