Reversible Block of Nerve Conduction by Ultrasound
- 1 January 1961
- journal article
- research article
- Published by American Medical Association (AMA) in Archives of Neurology
- Vol. 4 (1) , 83-89
- https://doi.org/10.1001/archneur.1961.00450070085009
Abstract
Introduction In recent years ultrasound has found a number of important applications to biological problems. In particular, its destructive effects on the nervous system promise to be of experimental as well as practical value.1-4In appropriate dosage it may enhance or depress the functional activity of the central nervous system.5,6Little is known about these functional effects, which do not necessarily involve the production of detectable lesions. This study on peripheral nerve was undertaken to investigate the effects of focused ultrasound on axonal conduction in a mixed nerve, and to shed light on the nature of the central effects. Methods The sciatic nerves of large green frogs were used. The branches in the thigh were cut and the main trunk with its tibial and peroneal extensions, measuring about 7 cm. in length, was removed. Distally the tibial and peroneal branches were tied together. The nerve was mounted inKeywords
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- FOCAL DESTRUCTION OF NERVOUS TISSUE BY FOCUSED ULTRASOUND: BIOPHYSICAL FACTORS INFLUENCING ITS APPLICATIONThe Journal of Experimental Medicine, 1956
- Production of Lesions in the Central Nervous System with Focused Ultrasound: A Study of Dosage FactorsThe Journal of the Acoustical Society of America, 1956
- STUDIES OF THE NERVE IMPULSEAmerican Journal of Physiology-Legacy Content, 1926