INHIBITION OF EXPERIMENTAL TUMOR-GROWTH IN HAMSTERS BY SMALL DIRECT CURRENTS

  • 1 January 1977
    • journal article
    • research article
    • Vol. 101  (6) , 294-297
Abstract
The effect of 3 electric current levels (3 mA, 500 .mu.A and 960 m.mu.A) on the growth of A-Mel-4 tumor was evaluated in hamsters as a mode of therapy. Direct current (DC) was applied for 1 h a day from the 3rd to 6th posttumor implant day by the introduction of a shielded point electrode directly into the tumor site. Tumor growth was inhibited, and metastases were reduced in the exposed animals. The higher DC levels produced necrosis in the tumors, and in several animals, the implantation site tumor was completely destroyed. These effects were most pronounced with the positive electrode.

This publication has 0 references indexed in Scilit: