Clinical performance of a new silver dressing, Contreet Foam, for chronic exuding venous leg ulcers
- 1 October 2003
- journal article
- clinical trial
- Published by Mark Allen Group in Journal of Wound Care
- Vol. 12 (9) , 351-354
- https://doi.org/10.12968/jowc.2003.12.9.26534
Abstract
Objective: This study aimed to evaluate the safety and performance of a new sustained silver-releasing dressing, Contreet Foam (Coloplast A/S), in the treatment of moderately to highly exuding chronic venous leg ulcers in which healing is delayed due to the presence of bacteria. Method: The clinical performance of Contreet Foam was studied for four weeks in 25 patients with moderately to highly exuding delayed-healing venous leg ulcers. Healing was assessed on a weekly basis with reference to the wound-bed tissue composition, degree of odour and pain, dressing performance and the dressing's effect on the peri-ulcer area. Blood samples were analysed for silver content. Results: Twenty-three out of 25 patients completed the study. One ulcer healed and no wound infections occurred during the study period. A mean 56% reduction in ulcer area (from 15.6 to 6.9cm2) was recorded during the four weeks, and there was a mean 25% reduction in granulation tissue from dull to healthy after one week. Wound odour reduced significantly after one week. Mean dressing wear time was 3.1 days, and there were only minimal incidences of leakage. Serum silver levels did not exceed reference values. Conclusion: Contreet Foam was found to be safe and performed well when used in the treatment of delayed-healing chronic venous leg ulcers, combining effective antibacterial properties with excellent exudate management. Declaration of interest: This study was supported by Coloplast A/S, Humlebæk, Denmark.Keywords
This publication has 11 references indexed in Scilit:
- Metallothioneins: potential therapeutic aids for wound healing in the skinWound Repair and Regeneration, 2002
- Silver 2: toxicity in mammals and how its products aid wound repairJournal of Wound Care, 2002
- Silver I: its antibacterial properties and mechanism of actionJournal of Wound Care, 2002
- A Matched-Pair, Randomized Study Evaluating the Efficacy and Safety of Acticoat* Silver-Coated Dressing for the Treatment of Burn WoundsJournal of Burn Care & Rehabilitation, 1998
- Silver aids healing in the sterile skin wound: experimental studies in the laboratory ratBritish Journal of Dermatology, 1997
- The use of two dressings for moderately exuding pressure soresJournal of Wound Care, 1994
- A comparative burn wound model in the New Yorkshire pig for the histopathological evaluation of local therapeutic regimens: silver sulfadiazine cream as a standardBritish Journal of Plastic Surgery, 1993
- Do burn patients have a silver lining?Burns, 1992
- Topical chemoprophylaxis with silver sulphadiazine and silver nitrate chlorhexidine creams: emergence of sulphonamide-resistant Gram-negative bacilli.BMJ, 1976
- Formation of the Scab and the Rate of Epithelization of Superficial Wounds in the Skin of the Young Domestic PigNature, 1962