Selective Monoalkylation of Ammonia: A High Throughput Synthesis of Primary Amines
- 1 November 1999
- journal article
- letter
- Published by Georg Thieme Verlag KG in Synlett
- Vol. 1999 (11) , 1781-1783
- https://doi.org/10.1055/s-1999-2946
Abstract
Primary amines are obtained in good to excellent yields by highly selective monoalkylation of ammonia with alkyl and aryl ketones using titanium(IV) isopropoxide and sodium borohydride.Keywords
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